Date: 19 January 2017 17:58
The 32-year-old midfielder was unable to complete Thursday's game as he was replaced by Andre Gomes at half-time
Andres Iniesta suffered a calf injury in Barcelona's Copa del Rey victory over Real Sociedad.
Barca confirmed after the first leg of the quarter-final tie that the midfielder had suffered the problem to his left calf and will undergo medical tests on Friday.
Simeone praises Atletico precision
Iniesta, 32, had been replaced by Andre Gomes at half-time, the latest blow in a season that has been interrupted by two knee injuries.
The match itself saw Luis Enrique's holders win 1-0, ending their curse at the Anoeta with a first win in nine attempts courtesy of Neymar's first-half penalty, delighting Sergio Busquets.
Final whistle! Barça win 1-0 in Anoeta against Real Sociedad thanks to Neymar's first half penalty #FCBlive #CopaFCB pic.twitter.com/MNXeaZaoxz— FC Barcelona (@FCBarcelona) January 19, 2017
"The team did themselves proud," Busquests said after the game.
"However, the tie is still to be decided. They [Real Sociead] are a good team."
The two teams play in the second leg at Camp Nou next Thursday, with Barca continuing their bid for a third straight Copa crown.